The conclusion that MMPs mediate the breaking down of sort II collagen Which aggrecan is destroyed by similar metalloproteinases called adamalysins with thrombospondin motifs (ADAMTSs) is supported by a substantial overall body of evidence [ten]. Though there is not any overcome for osteoarthritis, there are many management procedures which can help https://www.theorthopaedicandpainpractice.com/all-you-need-to-know-about-osteoarthritis/